Prostate Glandular Acinus
Submission Date: 12/19/2024
Modify Date: 7/9/2025
Prostate Glandular Acinus
BIOART-000577
Category:
Anatomy, Cells and Organelles
Description
This functional tissue unit (FTU) illustration includes cell types related to the prostate glandular acinus FTU in the ASCT+B Table Prostate v1.1. Multiple histology atlases, especially Netter’s Essential Histology with Correlated Histopathology (Ovalle, Nahirney, and Netter 2021) and Histology: A Text and Atlas (Wojciech Pawlina and Michael H. Ross 2019) were referenced. Cell types and measurements were referenced from Henry et al. 2018 and Fullwood et al. 2019. Uberon describes this FTU as follows: "A saclike structure of the prostate gland, comprised of at least three cell layers: an innermost layer of secretory columnar luminal epithelium, a middle layer of squamous basal epithelium that also contains neuroendocrine cells, transit amplifying cells, and stem cells, and an outer layer of smooth muscle intermixed with other stromal cells."
Bibliography:
- Fullwood, Nigel J., Alan J. Lawlor, Pierre L. Martin-Hirsch, Shyam S. Matanhelia, and Francis L. Martin. 2019. “An Analysis of Benign Human Prostate Offers Insights into the Mechanism of Apocrine Secretion and the Origin of Prostasomes.” Scientific Reports 9 (1): 4582. https://doi.org/10.1038/s41598-019-40820-2.
- Henry, Gervaise H., Alicia Malewska, Diya B. Joseph, Venkat S. Malladi, Jeon Lee, Jose Torrealba, Ryan J. Mauck, et al. 2018. “A Cellular Anatomy of the Normal Adult Human Prostate and Prostatic Urethra.” Cell Reports 25 (12): 3530-3542.e5. https://doi.org/10.1016/j.celrep.2018.11.086.
- Ovalle, William K., Patrick C. Nahirney, and Frank H. Netter. 2021. Netter’s Essential Histology: With Correlated Histopathology. Third edition. Philadelphia, PA: Elsevier.
- Wojciech Pawlina and Michael H. Ross. 2019. “Histology: A Text and Atlas: With Correlated Cell and Molecular Biology. Eighth Edition, 2018 Authors: Wojciech Pawlina; Michael H. Ross.” Morphologia 13 (4): 76–89. https://doi.org/10.26641/1997-9665.2019.4.76-89.
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Cite This Entry
Human Reference Atlas. (12/19/2024). Prostate Glandular Acinus. NIAID NIH BIOART Source. bioart.niaid.nih.gov/bioart/577
Keywords
Prostate Glandular Acinus
Collection
Human Reference Atlas
Category
Anatomy, Cells and Organelles
